Bone age assessment currently involves labor-intensive tasks such as tedious measurements, image comparisons, and the use of the Greulich & Pyle reference atlas. These processes demand high levels of focus and precision from human operators. Moreover, the current methods are time-intensive and manual analysis methods introduce significant variability both within and between different readers.
PANDA offers rapid results within the existing workflow, reducing calculation time compared to manual Greulich and Pyle atlas lookup. It delivers precise adult height estimation and accurate bone age estimation based on the Greulich and Pyle atlas.
of radiologists would use IB Lab PANDA for bone age estimation of hand radiographs if cost were no issue
of radiologists perceive IB Lab PANDA to be useful in their medical practice
PANDA’s Bone age estimation based on G&P is precise to ±4.2 months [3][5]
PANDA provides a swift automated method to estimate bone age according to Greulich & Pyle in a standardized form to facilitate the monitoring of child growth and development.
Radiological findings, measurements, and results including:
IB Lab PANDA uses deep learning technology to report bone age based on the Greulich & Pyle scale and saves time by presenting the results within 5 seconds. The system is to be used by trained medical professionals including, but not limited to, orthopedists and radiologists. It should not be used in-lieu of full patient evaluation or solely relied upon to make or confirm a diagnosis.
[1] King, D. G., Steventon, D. M., O'sullivan, M. P., Cook, A. M., Hornsby, V. P. L., Jefferson, I. G., & King, P. R. (1994). Reproducibility of bone ages when performed by radiology registrars: an audit of Tanner and Whitehouse II versus Greulich and Pyle methods. The British journal of radiology, 67(801), 848-851.
[2] Serinelli, S., Panetta, V., Pasqualetti, P., & Marchetti, D. (2011). Accuracy of three age determination X-ray methods on the left hand-wrist: a systematic review and meta-analysis. Legal medicine, 13(3), 120-133.
[3] Greulich, W. W., & Pyle, S. I. (1959). Radiographic atlas of skeletal development of the hand and wrist (2nd edition). Stanford Univ. Press.
[4] Bayley, N., & Pinneau, S. R. (1952). Tables for predicting adult height from skeletal age: revised for use with the Greulich-Pyle hand standards. The Journal of Pediatrics, 40(4), 423–441.
[5] IB Lab Clinical Validation study
[6] Halabi SS, Prevedello LM, Kalpathy-Cramer J, Mamonov AB, Bilbily A, Cicero M, Pan I, Pereira LA, Sousa RT, Abdala N, Kitamura FC, Thodberg HH, Chen L, Shih G, Andriole K, Kohli MD, Erickson BJ, Flanders AE. The RSNA Pediatric Bone Age Machine Learning Challenge. Radiology. 2019 Feb;290(2):498-503. doi: 10.1148/radiol.2018180736. Epub 2018 Nov 27. PMID: 30480490; PMCID: PMC6358027.
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